Approach to Hypertriglyceridemia-Induced Pancreatitis

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During today’s noon report, we discussed a case of hypertriglyceridemia-induced pancreatitis. Key points covered include:

  • Pathophysiology: Elevated triglycerides (>11.2 mmol/L) lead to the release of toxic free fatty acids, causing pancreatic inflammation.
  • Diagnosis: Two out of three criteria: abdominal pain, elevated lipase, and characteristic imaging findings. Elevated triglycerides are a key differentiator.
  • Management: Focus on fluid resuscitation, IV insulin to lower triglycerides, and early enteral feeding to maintain gut integrity.
  • Advanced Therapies: Consider therapeutic plasma exchange in severe cases or when triglyceride levels are refractory to medical therapy

Check out the full slide deck [here]!

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